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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
13.5 DPC

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Isl1  ISL1 transcription factor, LIM/homeodomain   (Synonyms: Islet 1)
Results  Reference
1*J:63174 Garces A, Haase G, Airaksinen MS, Livet J, Filippi P, deLapeyriere O, GFRalpha 1 is required for development of distinct subpopulations of motoneuron. J Neurosci. 2000 Jul 1;20(13):4992-5000
1*J:86049 Gavalas A, Ruhrberg C, Livet J, Henderson CE, Krumlauf R, Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes. Development. 2003 Dec;130(23):5663-79
1J:83128 Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, de Angelis MH, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE, Fisher EM, Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science. 2003 May 2;300(5620):808-12
1*J:198000 Hoffmann S, Berger IM, Glaser A, Bacon C, Li L, Gretz N, Steinbeisser H, Rottbauer W, Just S, Rappold G, Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia. Basic Res Cardiol. 2013;108(2):339
1J:224507 Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, Zhang X, Evans SM, Cui Y, Cui S, LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3. BMC Biol. 2014;12:25
1J:147041 Matsuyama M, Aizawa S, Shimono A, Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium. PLoS Genet. 2009 Mar;5(3):e1000427
1J:63340 Mikaels A, Livet J, Westphal H, De Lapeyriere O, Ernfors P, A dynamic regulation of GDNF-family receptors correlates with a specific trophic dependency of cranial motor neuron subpopulations during development. Eur J Neurosci. 2000 Feb;12(2):446-56
1J:84976 Pattyn A, Vallstedt A, Dias JM, Sander M, Ericson J, Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Development. 2003 Sep;130(17):4149-59
1J:162560 Qu Y, Glasco DM, Zhou L, Sawant A, Ravni A, Fritzsch B, Damrau C, Murdoch JN, Evans S, Pfaff SL, Formstone C, Goffinet AM, Chandrasekhar A, Tissir F, Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. J Neurosci. 2010 Jul 14;30(28):9392-401
1J:97218 Rossel M, Loulier K, Feuillet C, Alonso S, Carroll P, Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons. Development. 2005 Mar;132(6):1175-85
1J:94050 Schwarz Q, Gu C, Fujisawa H, Sabelko K, Gertsenstein M, Nagy A, Taniguchi M, Kolodkin AL, Ginty DD, Shima DT, Ruhrberg C, Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve. Genes Dev. 2004 Nov 15;18(22):2822-34
1J:166526 Shum AS, Tang LS, Copp AJ, Roelink H, Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube. Dev Dyn. 2010 Dec;239(12):3192-203
1J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4
1J:160731 Vivancos V, Chen P, Spassky N, Qian D, Dabdoub A, Kelley M, Studer M, Guthrie S, Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases. Neural Dev. 2009;4:7
1J:107396 Yang L, Cai CL, Lin L, Qyang Y, Chung C, Monteiro RM, Mummery CL, Fishman GI, Cogen A, Evans S, Isl1Cre reveals a common Bmp pathway in heart and limb development. Development. 2006 Apr;133(8):1575-85
1J:252306 Zakaria S, Mao Y, Kuta A, de Sousa CF, Gaufo GO, McNeill H, Hindges R, Guthrie S, Irvine KD, Francis-West PH, Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity. Curr Biol. 2014 Jul 21;24(14):1620-1627

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory